The inability to manage weight gain and weight regain throughout life is helping to fuel the obesity epidemic in adults and children throughout Europe. However, the successful participation of more than 400 families in eight countries in the largest European dietary intervention study, coordinated by the EC funded Diogenes project and headed by Professor Arne Astrup from the Faculty of Life Sciences at University of Copenhagen, is helping to address this vital issue.

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Researchers at the University of Illinois at Chicago have discovered how some bacteria can survive antibiotic treatment by turning on resistance mechanisms when exposed to the drugs.(original article)

AstraZeneca today announced that it submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for approval of a new indication for SYMBICORT (budesonide/formoterol fumarate dihydrate) Inhalation Aerosol for the treatment of patients with Chronic Obstructive Pulmonary Disease (COPD). SYMBICORT is currently approved for the long-term maintenance treatment of asthma in patients 12 years and older.(original article)

ISTA Pharmaceuticals, Inc. has announced positive results from the preliminary analysis of its second and final Bepreve (bepotastine ophthalmic solution) Phase III clinical study.(original article)

The known association of alcohol consumption with an increased risk of breast cancer has been linked by researchers at the University at Buffalo to a process that causes genes that promote normal cell growth to produce proteins that precipitate unregulated cell growth, an action known as hypermethylation(original article)

A report released on Sunday by a task force of the Association of American Medical Colleges that recommends new restrictions on what physicians, staff members and students at U.S. medical schools can accept from drug companies and medical device makers is “encouraging,” but it “flinched” on some important issues, a New York Times editorial states (New York Times, 4/29).(original article)

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The U.S. Food and Drug Administration today approved Amitiza (lubiprostone) for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C) in adult women aged 18 and over.(original article)

A JDRF collaboration between Johns Hopkins researchers and Genentech has shown that a drug for the treatment of diabetic eye disease has performed better in clinical trials than the current standard treatment using laser surgery.(original article)

All 129 U.S. medical schools should not allow pharmaceutical and medical device companies to provide food, gifts and travel to physicians, faculty members and students, according to a report released on Sunday by the Association of American Medical Colleges, the New York Times reports.(original article)

An article published in the April issue of the Journal of Alzheimer’s Disease presents a detailed characterization of a new drug discovery tool for Alzheimer’s disease.(original article)

In a clinical trial at The Children’s Hospital of Philadelphia, researchers from The University of Pennsylvania have used gene therapy to safely restore vision in three young adults with a rare form of congenital blindness.(original article)

Janet Woodcock, director of the Center for Drug Evaluation and Research at FDA, on Thursday at a Senate hearing said that the number of medication ingredients manufactured abroad limits the ability of the agency to ensure the safety of all treatments sold in the U.S., CQ HealthBeat reports (Carey, CQ HealthBeat, 4/24).(original article)

An old, fickle therapy for a variety of autoimmune diseases is getting a makeover, thanks to a decade-long investigation by Rockefeller University researchers.(original article)

Latona Life Sciences Inc. announced today that it has entered into two agreements for the acquisition of patent rights and orphan drug status to a novel late-stage drug, trademarked “Oralgam,” for the treatment of Juvenile and Adult Rheumatoid Arthritis.(original article)

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Amneal Pharmaceuticals, LLC has announced the execution of an Asset Purchase Agreement for Amneal’s wholly-owned subsidiary, Amneal Pharmaceuticals of New York, LLC, to acquire the assets, facilities and business of Interpharm. The acquisition includes Interpharm’s facilities on Long Island, New York as well as the intellectual property including ANDA’s, technology and processes.(original article)